Physical Activity and Inflammatory Bowel Disease Risk in UK Biobank Cohort

Yitian Wei published a dataset on figshare in May 2026 containing results from a prospective cohort study of 293,578 UK Biobank participants. The data analyzes the longitudinal association between self-reported physical activity intensity and the incidence of Crohn's disease and ulcerative colitis, using multivariable Cox regression models.

Use Cases

• Assessing the protective effect of total physical activity on Crohn's disease risk based on the study results.
• Investigating the nuanced, intensity-dependent relationship between activity and ulcerative colitis risk described in the findings.
• Validating or comparing results on the association between moderate-to-vigorous activity and IBD incidence.
• Examining the potential non-linear associations between physical activity levels and disease progression using the described statistical methods.

Strengths

• Large-scale study with 293,578 participants from the UK Biobank.
• Prospective cohort design with follow-up and linkage to hospital admission and death registry records.
• Analysis includes multivariable Cox regression and restricted cubic spline curves for non-linear associations.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data relies on self-reported physical activity measures, which may introduce bias.

Provenance

Source

UK Biobank

Collection Method

Prospective cohort study analyzing self-reported physical activity and linked hospital/death records.

Freshness

Last updated 2026-05-14 05:23:56; freshness should be verified.

Geography

United Kingdom