Sepsis-Induced ARDS Patient Data with Glucose-Lymphocyte Ratio Biomarker

2,485 patient records from the MIMIC-IV database form a derivation cohort for a study on sepsis-induced acute respiratory distress syndrome. The research investigates the glucose-to-lymphocyte ratio as a novel composite biomarker for predicting 28-day mortality. An external validation cohort of 298 patients from a Chinese hospital was used to confirm findings.

Use Cases

• Predicting 28-day mortality risk in sepsis-induced ARDS patients based on glucose-lymphocyte ratio values.
• Evaluating the incremental prognostic value of a biomarker over established scores like APS III and SAPS II.
• Conducting subgroup analyses to identify patient populations where biomarker performance varies.
• Building multivariable Cox proportional hazards models for clinical risk stratification.

Strengths

• Derivation cohort contains 2,485 patient records from the MIMIC-IV database.
• External validation was performed using an independent cohort of 298 patients.
• Analysis includes multiple statistical methods: LASSO-Boruta selection, Cox models, ROC, and DCA.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count for the actual dataset file is unknown, which may limit suitability assessment.
• The data likely reflects bias inherent to retrospective cohort studies from specific hospital databases.

Provenance

Source

MIMIC-IV database and Affiliated Hospital of Xuzhou Medical University.

Collection Method

Multicenter retrospective cohort analysis.

Freshness

Last updated 2026-03-19 06:34:34; freshness should be verified.