TyG Index Association with H. pylori Infection in 705 Hospitalized Patients

A cross-sectional study of 705 hospitalized patients, with 238 testing positive for Helicobacter pylori (33.8%). The dataset, authored by Yu Zhou and last updated in May 2026, examines associations between triglyceride-glucose indices and H. pylori infection status and bacterial load.

Use Cases

• Modeling the association between triglyceride-glucose index (TyG) and H. pylori infection status based on logistic regression results.
• Analyzing potential nonlinear dose-response patterns between metabolic indices and infection using restricted cubic splines.
• Investigating subgroup interactions, such as the effect of BMI or age on the TyG-H. pylori association.
• Exploring the relationship between bacterial load (delta over baseline) and metabolic indices among H. pylori-positive individuals.

Strengths

• Includes data from 705 participants, with 238 H. pylori-positive cases.
• Analysis includes sensitivity, subgroup, and interaction analyses stratified by age and BMI.
• Results are reported with specific odds ratios, confidence intervals, and p-values (e.g., OR 1.472, 95% CI 1.096–1.978).

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• Data is from a single center's hospitalized patients, which may reflect specific population biases.
• The dataset is very small at 26.9 KB, indicating limited scope.

Provenance

Source

figshare, authored by Yu Zhou.

Collection Method

Retrospective screening of hospitalized patients at a single center, using 13C-urea breath test for H. pylori diagnosis.

Freshness

Last updated 2026-05-08 05:56:44; freshness should be verified.