BCS2.0: Bacterial Species and AMR Gene Detection Data from Clinical Samples

A dataset describing the BCS2.0 capture sequencing platform for rapid differential diagnosis of bacterial infections and antimicrobial resistance. The data likely contains results from analytical validation using 20 bacterial strains in contrived plasma and urine samples, with performance measures including limits of detection and assay reproducibility. The dataset was authored by Amit Ranjan and last updated on April 20, 2026.

Use Cases

• Benchmarking diagnostic assay sensitivity based on the described limit of detection of 5 colony-forming units per milliliter
• Training models for mixed infection detection based on the platform's capability mentioned in the description
• Validating metagenomic classification pipelines based on the probe design covering 894 pathogenic bacterial species and AMR genes
• Comparing diagnostic concordance based on results validated against MALDI and BCID assays

Strengths

• Probe design covers 894 known or potential pathogenic bacterial species from the MetaPhlAn4 database
• Analytical validation confirmed a limit of detection of 5 colony-forming units per milliliter
• Results were concordant with established methods like MALDI and BCID assays
• Dataset is openly shared under a CC-BY-4.0 license

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download
• The dataset is very small (17.3 KB), suggesting it may contain summary results or a description rather than extensive raw sequencing data
• Freshness should be verified as the last update date is in the future (2026-04-20)

Provenance

Source

figshare

Collection Method

Data likely generated from the BCS2.0 capture sequencing platform performance validation using contrived and clinical samples.

Time Range

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Freshness

Last updated 2026-04-20 05:23:11; freshness should be verified.

Geography

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