Table 2_BKI-1748: Efficacy Data Against Ovine Congenital Toxoplasmosis

BKI-1748 treatment initiated after IgM seroconversion in pregnant sheep resulted in 91% viable lambs, compared to 52% in untreated animals. The dataset, authored by Roberto Sánchez-Sánchez and last updated in April 2026, contains results from a study of 23 infected and 3 uninfected sheep. Only 17% of lambs in the treated group were congenitally infected, versus 100% in the untreated control group.

Use Cases

• Analyzing drug efficacy based on lamb viability and infection rates described in the study
• Comparing IgG seroconversion timelines between treated and untreated animal groups
• Evaluating treatment outcomes for congenital toxoplasmosis based on birth weight data
• Modeling prenatal intervention strategies initiated after specific immunological markers

Strengths

• Results include specific efficacy metrics: 91% vs. 52% lamb viability and 17% vs. 100% congenital infection rates.
• Study design details are provided, including a treatment group of 10 sheep and a control group of 10.
• The dataset is shared under a permissive CC-BY-4.0 license for reuse.

Limitations

• The dataset is a 171.1 KB DOCX file, indicating a very limited scope, likely a single table or summary.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

figshare

Collection Method

Experimental study involving oral inoculation of sheep with Toxoplasma gondii oocysts and subsequent drug treatment.

Freshness

Last updated 2026-04-27 05:18:19