Bushen Huoxue Recipe Study: Transcriptomic and Pharmacological Data on RSA Intervention

155 chemical constituents of Bushen Huoxue Recipe were identified alongside 267 therapeutic targets for recurrent spontaneous abortion. Transcriptome sequencing and network pharmacology analyses suggest the PI3K/AKT pathway is a key mechanism for intervention. The dataset, authored by Jingheng You and last updated in April 2026, includes results from a mouse miscarriage model.

Use Cases

• Analyze the relationship between cell proliferation pathways and recurrent spontaneous abortion based on transcriptome sequencing results
• Identify potential therapeutic targets for miscarriage based on the 267 targets identified via network pharmacology
• Study the interaction between herbal compounds and key signaling pathways based on the identified 155 chemical constituents

Strengths

• 155 chemical constituents of the Bushen Huoxue Recipe formula were identified
• 267 therapeutic targets for recurrent spontaneous abortion were mapped
• Experimental results include statistically significant changes in embryonic loss rate and hormone levels (p < 0.01, p < 0.05)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is a single 18.5 KB document, indicating a limited scope of raw data

Provenance

Source

figshare

Collection Method

UPLC–Q–TOF–MS/MS for compound identification, transcriptome sequencing, network pharmacology, and in vivo mouse model experiments.

Freshness

Last updated 2026-04-21 05:36:17