CAR-T Cell Therapy Clinical Trials in Non-Hodgkin Lymphoma: 360 Trials Landscape

360 clinical trials for CAR-T cell therapy in non-Hodgkin lymphoma, systematically analyzed from the Trialtrove database up to December 18, 2025. The dataset was created by Jinyu Wu and published on figshare under a CC-BY-4.0 license, with a last update in May 2026. It describes trial characteristics including status, phase, location, sponsor type, molecular targets, and endpoints.

Use Cases

• Analyzing geographic distribution and sponsor types of CAR-T trials based on the described trial characteristics.
• Tracking the diversification of molecular targets beyond CD19 based on the landscape analysis.
• Assessing the focus on safety versus long-term efficacy endpoints based on the reported endpoint prioritization.
• Mapping the phase distribution and trial status to understand the clinical development pipeline.

Strengths

• Systematically extracted from the Trialtrove database using predefined criteria.
• Includes 360 eligible clinical trials, providing a substantial sample for analysis.
• Covers multiple key trial characteristics such as phase, location, and targets.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific analytical tasks.
• The dataset is 3.1 MB, which is a small scale and may limit the depth of analysis.

Provenance

Source

Trialtrove database

Collection Method

Systematic landscape analysis using predefined search and screening criteria.

Time Range

Trials registered up to December 18, 2025.

Freshness

Last updated 2026-05-08 05:48:17; freshness should be verified.

Geography

Global, but activity is described as concentrated in a limited number of countries.