Post-Stroke Hemorrhagic Infarction Case Report in a Beagle Dog

A 658.1 KB case report details the acute neuropathology of a 4.5-year-old male Beagle with status epilepticus and post-stroke hemorrhagic infarction. The report includes clinical course, hematobiochemical analysis, treatment details, and gross and histopathological findings. Author Nikita M. Joshi published the report on figshare in March 2026.

Use Cases

• Analyze the correlation between serum creatine kinase and aspartate aminotransferase levels and the severity of muscular exertion and neuroinflammatory response.
• Investigate the expression of VEGF-A and reticulin in newly formed peri-infarct vessels as a marker for acute vascular proliferation.
• Compare histopathological findings of multifocal thrombosis and liquefactive necro-hemorrhagic foci with clinical seizure refractoriness.
• Study the potential of post-stroke epilepsy features as tissue-based markers for detecting seizure recurrence via advanced imaging.

Strengths

• Provides a detailed, single-subject case report with comprehensive clinical and pathological data.
• Includes specific quantitative findings such as a 30% decline in serum albumin levels and marked enzyme elevations.
• Contains histopathological analysis confirming acute processes like VEGF-A expression and absence of mature collagen.

Limitations

• Extremely limited scope as a single-case report (n=1), preventing statistical analysis or generalization.
• Data is presented in a narrative DOCX format, not structured tabular data, requiring manual extraction for analysis.
• Findings are specific to one 4.5-year-old male Beagle, which may not represent broader canine or veterinary populations.

Provenance

Source

figshare, author Nikita M. Joshi.

Collection Method

Clinical case report and post-mortem pathological analysis.

Time Range

Covers the clinical course and necropsy of a single case.

Freshness

Last updated March 2026.

Geography

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