Synovial Sarcoma Case Report: Myxoid Stroma and Absent Epithelial Differentiation

A figshare-hosted case report authored by Tomohiro Miyazaki details a rare presentation of synovial sarcoma in a 61-year-old woman's thigh. The report, last updated in May 2026, describes the tumor's myxoid histology, diagnostic challenges, and molecular confirmation via SS18–SSX1 fusion gene identification. It is a single-case document of 661.4 KB, licensed under CC-BY-4.0.

Use Cases

• Studying histological mimics in soft-tissue sarcomas based on the description of myxoid stroma resembling extraskeletal myxoid chondrosarcoma.
• Investigating the diagnostic utility of molecular analyses like FISH and RT-PCR based on the case's use of these methods for confirmation.
• Analyzing the correlation between immunohistochemical marker expression (e.g., cytokeratin, SOX9) and tumor phenotype based on the reported findings.

Strengths

• Includes specific molecular diagnostic results, such as the identification of an SS18–SSX1 fusion gene.
• Provides detailed clinical and pathological data for a single, well-documented case, including patient age (61), tumor size (55 mm), and location (right thigh).
• The document is licensed under CC-BY-4.0, permitting open sharing and adaptation.

Limitations

• Row count is unknown, which may limit suitability assessment; the dataset is a single case report.
• Column-level documentation is absent; field semantics must be inferred after download.
• The data is a single case study, limiting statistical power and generalizability.

Provenance

Source

figshare, author Tomohiro Miyazaki.

Collection Method

Likely a clinical case report documenting patient diagnosis, treatment, and molecular analysis.

Freshness

Last updated 2026-05-29 04:52:17; freshness should be verified.