Table 2_Changes in incretin hormone concentrations after pancreaticoduodenectomy: a system

Oliwia Grząsiak-Kraj's systematic review and exploratory meta-analysis examines changes in glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) after pancreaticoduodenectomy. The work synthesizes evidence from six human studies involving 134 participants, identified from PubMed, Embase, and Scopus between 2000 and 2026. The meta-analysis component is explicitly exploratory, based on only two comparable studies.

Use Cases

• Reviewing clinical evidence on postprandial GLP-1 and GIP changes based on the systematic review of six studies.
• Comparing hormonal outcomes between Whipple and pylorus-preserving pancreaticoduodenectomy based on the exploratory meta-analysis.
• Investigating co-reported metabolic measures like glucose, insulin, and gastric emptying mentioned in the review results.

Strengths

• Follows PRISMA 2020 guidelines for systematic review methodology.
• Includes data from 134 participants across six identified studies.
• Registered with PROSPERO (identifier 1345848).

Limitations

• The meta-analysis is explicitly exploratory and based on only two studies, making pooled estimates fragile.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Oliwia Grząsiak-Kraj via figshare

Collection Method

Systematic literature review of PubMed, Embase, and Scopus, followed by an exploratory meta-analysis.

Time Range

Studies published from 1 January 2000 to 27 March 2026

Freshness

Last updated 2026-06-03 12:49:47; freshness should be verified.