Streptomyces sp. NELs-40 Genomic and Antibacterial Efficacy Data

A 7,973,786 bp genome of Streptomyces sp. NELs-40 harbors 49 biosynthetic gene clusters, 30 of which are linked to antimicrobial compounds. The ethyl acetate extract demonstrated potent activity against MRSA ATCC 43300, with a 37 mm inhibition zone and an MIC of 125 μg/mL. This dataset, authored by Mamy Jayne Nelly Rajaofera and last updated in May 2026, presents genomic characterization and antibacterial assay results from a study on a novel antimicrobial source.

Use Cases

• Comparative genomic analysis based on the reported 16S rRNA, ANI, AAI, and dDDH values against reference genomes.
• Identifying potential antimicrobial biosynthetic gene clusters based on the 30 BGCs predicted by antiSMASH.
• Evaluating antibacterial efficacy against MRSA based on the reported MIC, inhibition zone, and biofilm inhibition data.
• Analyzing bioactive metabolite composition based on the 23 compounds identified via GC–MS analysis.

Strengths

• Genomic data includes a complete 7,973,786 bp assembly with 6,872 protein-coding genes and 49 biosynthetic gene clusters.
• Antibacterial efficacy is quantified with specific metrics: 37 mm inhibition zone, MIC of 125 μg/mL, and 32.25% biofilm inhibition.
• Bioactive metabolite analysis identified 23 specific compounds, including 9-octadecenoic acid methyl ester and pyrrolo[1,2-a]pyrazine-1,4-dione derivatives.

Limitations

• The dataset is a 20.8 KB DOCX file, suggesting limited raw data and likely consisting of a summary table or manuscript.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for computational analysis.

Provenance

Source

figshare, authored by Mamy Jayne Nelly Rajaofera.

Collection Method

Data generated from genomic sequencing (Illumina HiSeq X10), bioinformatic analysis (antiSMASH, CompareM, TYGS), and laboratory assays (well diffusion, MIC, GC–MS).

Freshness

Last updated 2026-05-29 06:07:47; freshness should be verified.