Gut Microbiota Dysbiosis Patterns Across Six Digestive System Cancers

59 systematic reviews synthesize gut microbiota changes associated with six distinct digestive system cancers. The data, compiled by Jing Wang, was extracted from studies published up to January 2025. This synthesis delineates a qualitative landscape of microbial imbalances, highlighting potential markers for early detection and targeted therapy.

Use Cases

• Identifying microbial signatures for specific cancer types based on reported phylum and genus-level changes.
• Comparing dysbiosis patterns across esophageal, gastric, colorectal, and pancreatic cancers as described in the review.
• Informing the design of multiomics studies for clinical translation, as suggested in the description.

Strengths

• Synthesizes findings from 59 distinct systematic reviews, providing a consolidated view.
• Focuses on six specific digestive system cancer types: esophageal, gastric, colorectal, pancreatic ductal adenocarcinoma, and others.
• Includes methodological quality assessment of included studies using the ROBIS tool.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 43.6 KB file size suggests a very limited scope, likely containing summary tables rather than raw data.

Provenance

Source

figshare, author Jing Wang.

Collection Method

Systematic review and data synthesis from four English and three Chinese databases.

Time Range

Studies included up to January 2025.

Freshness

Last updated 2026-04-28 05:28:13; freshness should be verified.