Chronic Thromboembolic Pulmonary Hypertension Patient Outcomes in Kazakhstan

110 adult patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) between 2018 and 2024 are analyzed in this clinical dataset. It compares management strategies and survival outcomes between patients undergoing pulmonary endarterectomy (PEA) and those receiving medical therapy alone. The data includes clinical characteristics, imaging findings, invasive hemodynamics, and a median follow-up of 39 months.

Use Cases

• Compare baseline hemodynamic parameters between surgical and medical therapy groups to assess patient selection criteria.
• Analyze the association between pulmonary endarterectomy (PEA) and improvements in exercise capacity and cardiac stress biomarkers from pre- to post-operative data.
• Evaluate long-term survival outcomes over a 39-month median follow-up period across different treatment cohorts.
• Assess the median delay from symptom onset to referral (24 months) in relation to patient outcomes and treatment efficacy.

Strengths

• Includes data from 110 consecutive adult patients, providing a substantive clinical cohort for analysis.
• Covers a 6-year time range (2018-2024) from the sole national referral center in Kazakhstan, offering a centralized view.
• Provides paired pre- and post-operative data for a subgroup, enabling within-patient analysis of surgical outcomes.
• Reports specific clinical metrics such as a median symptom-to-referral delay of 24 months and a median follow-up of 39 months.

Limitations

• The dataset is relatively small with 110 patients, limiting the statistical power for subgroup analyses and survival comparisons.
• As a single-center study from Kazakhstan, findings may not be generalizable to other populations or healthcare systems.
• Sample data and column definitions are unavailable, which complicates understanding the dataset's exact structure and variables.

Provenance

Source

Sole national CTEPH referral center in Kazakhstan.

Collection Method

Retrospective analysis of consecutive adult patients diagnosed with CTEPH.

Time Range

2018 to 2024

Freshness

Data covers patients up to 2024, with the record last updated in March 2026.

Geography

Kazakhstan, Central Asia