ST3672 NDM-1-Producing Vibrio Parahaemolyticus: Clinical and Genomic Characterization

A novel, multidrug-resistant Vibrio parahaemolyticus strain (VP1434) was isolated from a patient in a food poisoning outbreak. The study by Chengpei Ni, uploaded in April 2026, includes whole-genome sequencing data, phylogenetic analysis, and mouse infection results. It reports resistance to 29 tested antibiotics and identifies 185 virulence factors in the strain.

Use Cases

• Studying the genomic basis of multidrug resistance based on the identified blaNDM-1-carrying plasmid and other resistance genes.
• Analyzing virulence factor profiles and pathogenicity based on the 185 identified factors, including tlh and trh.
• Tracing the evolutionary relationships of emerging bacterial strains based on the phylogenetic analysis of global V. parahaemolyticus isolates.
• Investigating plasmid transfer and horizontal gene spread based on the described conjugation experiments with recipient strain VP0577.

Strengths

• Includes detailed phenotypic data from testing against 29 antibiotics.
• Provides whole-genome sequencing data enabling analysis of resistance genes and virulence factors.
• Contains experimental validation of pathogenicity through mouse infection models.

Limitations

• The dataset is a single 18.9 KB DOCX document; the underlying genomic sequence data files are not directly available.
• Row count and column-level documentation are absent; data structure must be inferred from the manuscript.
• Focuses on a single clinical isolate (VP1434), limiting generalizability.

Provenance

Source

Chengpei Ni, via figshare.

Collection Method

Clinical isolate from a food poisoning outbreak, analyzed via antimicrobial susceptibility testing, whole-genome sequencing, and mouse infection experiments.

Freshness

Last updated 2026-04-22 05:48:32.