Meta-Analysis of 50 PCI Trials with 39,863 Patient Outcomes

Network meta-analysis of 50 randomized studies involving 39,863 patients, comparing outcomes of five percutaneous coronary intervention guidance strategies. It reports comparative risk ratios for major adverse cardiovascular events, mortality, and other clinical endpoints.

Use Cases

• Compare major adverse cardiovascular events (MACE) risk ratios between angiography, FFR, iFR, IVUS, and OCT guidance strategies.
• Analyze the association of all-cause mortality and cardiac death risk estimates with physiology-guided iFR versus IVUS.
• Rank guidance modalities using SUCRA values based on outcomes like myocardial infarction and stent thrombosis.

Strengths

• Analysis is based on 50 randomized studies, providing a substantial evidence base.
• Includes data from 39,863 patients, with gender breakdowns provided (29,571 male, 10,031 female).
• Reports specific patient counts per guidance modality (e.g., 15,463 angiography-guided, 10,728 IVUS-guided).

Limitations

• The underlying data is a summary meta-analysis; raw patient-level data is not provided.
• The dataset is a 38.4 KB DOCX file, limiting direct computational analysis without text extraction.
• Comparative findings are based on aggregated study results, which may mask individual trial heterogeneity.

Provenance

Source

figshare, authored by Yuancheng Jin.

Collection Method

Systematic review and network meta-analysis of 50 randomized studies.

Freshness

Last updated March 20, 2026.