Bovine Sperm Proteomic Profiles Before and After Cryopreservation

A proteomic analysis of bovine sperm from five fertile bulls, comparing fresh and cryopreserved states. The study identified 1,373 proteins and found 84 with significant differential abundance. The data was published by Alexandra Keller on figshare in 2026.

Use Cases

• Identify protein biomarkers for sperm cryosurvival based on differential abundance analysis.
• Model pathways disrupted during cryopreservation based on functional enrichment results.
• Validate proteomic findings with image-based cytometry data mentioned in the description.

Strengths

• Includes data from five sexually mature bulls with proven fertility, providing a relevant biological sample.
• Identifies 84 proteins with significant differential abundance (log2FC > 2, p < 0.05), offering clear targets for analysis.
• Released under a CC-BY-4.0 license, permitting open reuse and modification.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (23.4 KB), indicating limited scope.

Provenance

Source

figshare, authored by Alexandra Keller.

Collection Method

Bottom-up proteomic approach using LC-MS/MS analysis on semen samples.

Time Range

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Freshness

Last updated 2026-04-16 05:26:13; freshness should be verified.

Geography

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