Comparative Transcriptome Analysis of Rhinolophus Bats for Antiviral Immune Signatures

Rhinolophus pusillus is a horseshoe bat species known to simultaneously harbor SARS-CoV and SARS-CoV-2 related coronaviruses. This 12.8 KB Excel dataset contains results from a multi-tissue transcriptome analysis of six R. pusillus and Rhinolophus ferrumequinum individuals, integrated with public RNA-seq data from other mammals. Author Lamei Zhao published the dataset under a CC-BY-4.0 license on figshare in May 2026.

Use Cases

• Identifying genes with elevated basal antiviral activity based on comparative transcriptomic analysis.
• Investigating tissue-specific regulatory modules using Weighted Gene Co-expression Network Analysis (WGCNA) results.
• Analyzing the role of long non-coding RNAs in immune regulation through lncRNA-mRNA network data.
• Comparing innate immune and inflammatory transcriptional programs between bat species.

Strengths

• Dataset is derived from a multi-species, multi-tissue comparative analysis integrating public RNA-seq data.
• Results focus on a specific bat species (Rhinolophus pusillus) identified as a key multi-virus reservoir.
• Analysis includes both protein-coding RNA and predicted long non-coding RNA (lncRNA) regulatory networks.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is very small (12.8 KB), suggesting it contains summary or processed results rather than raw sequencing data.

Provenance

Source

figshare

Collection Method

Multi-tissue transcriptome generation and cross-species comparative transcriptomic analysis.

Time Range

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Freshness

Last updated 2026-05-20 04:35:00

Geography

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