CrpH Protein Data for Bordetella Pertussis Heme-Copper Oxidoreductase Function

Majda Hachmi published a dataset on figshare in March 2026, analyzing the CrpH protein in Bordetella pertussis. The 1.2 MB Excel file contains data from in vitro and in vivo experiments, transcriptomics, and in silico analyses. The research characterizes CrpH as a prototype PepSY_TM protein that supports heme-copper oxidoreductase function in bacterial respiration.

Use Cases

• Training models to predict protein function based on sequence similarity networks mentioned in the description.
• Analyzing the relationship between copper starvation and gene expression based on transcriptomic data.
• Studying the structural motifs of PepSY_TM family proteins based on heme-binding motif analysis.
• Investigating synthetic genetic interactions based on the phenotype of the double crpH-ccoG mutant.

Strengths

• Data is licensed under CC-BY-4.0, allowing for broad reuse.
• Dataset is relatively fresh, last updated on 2026-03-18.
• Analysis combines multiple experimental approaches: in vitro, in vivo, transcriptomics, and in silico.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Dataset is small (1.2 MB), which may limit the scope of analysis.

Provenance

Source

figshare

Collection Method

Data generated from laboratory experiments (in vitro, in vivo), transcriptomics, and computational (in silico) analyses.

Freshness

Last updated 2026-03-18 06:42:29