Meta-Analysis of Menstrual Blood HPV Test Accuracy for Cervical Cancer Screening

Seven studies involving 1,672 adult women were included in this meta-analysis examining the diagnostic accuracy of self-collected menstrual blood for high-risk HPV testing. The analysis, conducted from October to November 2024 by Xuechao Ji, reports an overall sensitivity of 0.96 and specificity of 0.53 for detecting cervical intraepithelial neoplasia and cervical cancer.

Use Cases

• Evaluating the performance of self-sampling screening methods based on reported sensitivity and specificity metrics.
• Informing public health policy on cervical cancer screening based on meta-analysis evidence.
• Designing future diagnostic studies based on the identified high sensitivity and low specificity of the test.

Strengths

• Includes data from 1,672 adult women aggregated from seven studies.
• Reports specific performance metrics: sensitivity of 0.96 (95% CI = 0.74-1.00) and specificity of 0.53 (95% CI = 0.11-0.91).
• Follows PRISMA guidelines for systematic review and uses bivariate random-effects and HSROC models for meta-analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (28.0 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of observational studies from PubMed, Embase, and Cochrane databases.

Time Range

Studies published through October 23, 2024; data analyzed October-November 2024.

Freshness

Last updated 2026-04-21 17:44:02; freshness should be verified.

Geography

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