Meta-Analysis of Astragalus mongholicus Bunge for Wound Healing in Animal Models

20 citations (21 studies) with data from 559 animals were included in this systematic review and meta-analysis. The study, authored by Jun Zhang and registered in PROSPERO, evaluates the efficacy and safety of the botanical drug Astragalus mongholicus Bunge for wound healing in preclinical animal models. It was last updated on 2026-04-17.

Use Cases

• Conducting secondary analysis of pooled effect sizes for wound contraction percentage based on the reported standardized mean difference.
• Reviewing methodological approaches for systematic reviews of preclinical animal studies using the SYRCLE tool.
• Identifying research gaps for future preclinical and clinical trials on botanical wound treatments based on the conclusions.

Strengths

• Includes data from 559 animals across 21 studies, providing a quantitative basis for analysis.
• Reports specific pooled effect metrics, such as a standardized mean difference of 4.18 for wound contraction.
• Follows a registered protocol (PROSPERO CRD420250641262) and uses a defined risk-of-bias assessment tool (SYRCLE).

Limitations

• The dataset is a 15.4 KB DOCX file, indicating a very limited scope, likely containing only the review manuscript.
• Row count and column-level documentation for any underlying data are unknown.
• The description focuses on the review's findings rather than the structure of any primary data tables.

Provenance

Source

Jun Zhang via figshare.

Collection Method

Systematic search of seven databases for randomized controlled studies in animal wound models.

Freshness

Last updated 2026-04-17 05:08:54.