Meta-Analysis of Drug-Coated Balloons vs. Drug-Eluting Stents for Coronary Artery Disease

Yuting Wang's meta-analysis compares the efficacy and safety of drug-coated balloons (DCB) versus drug-eluting stents (DES) for coronary artery disease. The dataset aggregates results from 23 randomized controlled trials comprising 8,123 patients, sourced from PubMed, Embase, CENTRAL, and Web of Science up to March 2026. It was last updated on May 18, 2026.

Use Cases

• Comparing target lesion revascularization rates between DCB and DES based on pooled odds ratios
• Analyzing lesion-specific outcomes for in-stent restenosis versus de novo lesions based on subgroup analyses
• Investigating the association between cardiac death risk and paclitaxel-coated versus sirolimus-coated balloons based on exploratory findings
• Evaluating treatment effects across different clinical presentations (STEMI, NSTEMI, unstable angina) based on interaction analyses

Strengths

• Aggregates data from 23 randomized controlled trials, a substantial evidence base
• Includes 8,123 patient records, providing a meaningful sample size for meta-analysis
• Conducts detailed subgroup analyses by lesion type, vessel size, clinical presentation, and DCB type

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The description notes exploratory findings with limited events and shorter follow-up for some subgroups, requiring cautious interpretation

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of randomized controlled trials from PubMed, Embase, CENTRAL, and Web of Science.

Time Range

Trials from inception to March 2026.

Freshness

Last updated 2026-05-18 05:53:52; freshness should be verified