QUIET Trial: Efficacy and Safety of Qingre Huatan Formula for Acute Ischemic Stroke

A 2025-2026 randomized controlled trial protocol for 72 patients with acute ischemic stroke. The study, authored by Xiangyi Zheng, investigates whether the Qingre Huatan Formula prevents early neurological deterioration within 7 days of stroke onset. The protocol includes primary and secondary outcomes measured using the NIHSS and modified Rankin Scale.

Use Cases

• Analyzing clinical trial design for stroke interventions based on the described randomized, double-blind, placebo-controlled methodology.
• Studying outcome measures for early neurological deterioration based on the NIHSS score increase criteria mentioned.
• Investigating the use of traditional Chinese medicine formulas in acute care settings based on the described Qingre Huatan Formula intervention.
• Examining follow-up schedules in stroke trials based on the 10-day treatment and 90-day follow-up period described.

Strengths

• The protocol is a structured, randomized, double-blind, placebo-controlled study, which suggests a rigorous design.
• Specific primary and secondary outcomes are defined, including NIHSS score changes and modified Rankin Scale scores.
• The dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.

Limitations

• The dataset is a 79.5 KB DOCX file containing a study protocol, not raw clinical trial data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative analysis.

Provenance

Source

figshare, authored by Xiangyi Zheng.

Collection Method

Likely contains the study protocol document for the QUIET clinical trial.

Time Range

The trial protocol was registered in February 2025.

Freshness

Last updated 2026-04-13 04:35:34; freshness should be verified.

Geography

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