Endometrial Organoid and Stromal Cell Genotyping Data from Uterus Transplant Recipients

Lisa M. Meisl published data on May 12, 2026, investigating the cellular origin of the endometrium after uterus transplantation. The dataset includes short tandem repeat (STR) profiling results from donor and recipient blood, endometrial organoids, and stromal cell cultures from four transplant cases, tracked for up to seven years. It provides evidence against bone marrow–derived cell contribution to endometrial regeneration.

Use Cases

• Validate endometrial cellular origin models based on donor-recipient genotyping data.
• Assess long-term donor-derived cell persistence in transplanted tissues based on data spanning up to seven years.
• Compare epithelial and stromal cell lineage contributions using data from separate 3D organoid and 2D stromal culture systems.

Strengths

• Data is derived from a unique donor-recipient model of four uterus transplantation cases.
• Samples include biopsies from before and after pregnancy, as well as from uterus explantation.
• Genotyping was performed using short tandem repeat (STR) profiling on genomic DNA.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 14.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Patient-derived 3D endometrial organoid and 2D stromal cell cultures were established from uterus transplant recipients, followed by STR profiling.

Time Range

Data spans up to seven years of follow-up from four transplant cases.

Freshness

Last updated 2026-05-12 05:43:14; freshness should be verified.