Genomic and Functional Analysis of Stress-Responsive Prophages in Lactobacillus helveticus

Andrea Mancini's dataset contains genomic and functional analysis data for six temperate bacteriophages isolated from Trentingrana natural whey starters. The data likely includes results from quantitative PCR and virion detection experiments investigating prophage induction under cheesemaking-related stresses like heat shock, nutrient limitation, lactic acid, and oxidative stress. The dataset was last updated on 2026-04-23.

Use Cases

• Modeling prophage induction dynamics based on stress type and intensity described in the study.
• Comparing genomic responses of different Lactobacillus helveticus phages to heat shock and acid stress.
• Investigating the decoupling between phage genome replication and virion release under various abiotic conditions.
• Analyzing the role of prophages as modulators of microbial population stability in natural whey starters.

Strengths

• Dataset is focused on a specific, well-described experimental system involving six isolated bacteriophages.
• Analysis covers multiple, relevant stress conditions (heat shock, nutrient limitation, lactic acid, oxidative stress).
• Data is associated with a detailed, peer-reviewed-style methodological description in the provided metadata.
• Available under a permissive CC-BY-4.0 license for reuse.

Limitations

• The dataset is very small at 24.5 KB, indicating limited scope or summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

Andrea Mancini, via figshare.

Collection Method

Data likely generated from isolating bacteriophages from Trentingrana natural whey starters and conducting qPCR and virion detection experiments.

Freshness

Last updated 2026-04-23 05:27:54; freshness should be verified.

Geography

Associated with Trentingrana cheese production; specific location not stated.