Lactococcus cremoris FBMS_5810: Genomic and Preclinical Evaluation Data

20.1 KB of genomic characterization and preclinical evaluation data for the probiotic candidate Lactococcus cremoris FBMS_5810, authored by Ioanna Farmakioti and last updated on April 29, 2026. The dataset includes results from in vivo mouse studies showing changes in gut microbiota composition and intestinal gene expression.

Use Cases

• Identify strain-specific genes for adhesion and colonization based on genomic analyses mentioned in the description
• Evaluate probiotic safety profiles based on preclinical evaluation data
• Analyze gut microbiota modulation effects based on changes in Muribaculaceae, Erysipelotrichaceae, and Streptococcaceae abundances
• Study host-microbe interactions based on changes in intestinal Tnf, Il1b, and Zo1 gene expression

Strengths

• Dataset integrates genomic characterization with in vivo preclinical evaluation, providing a multi-faceted view.
• Specific microbial families (e.g., Muribaculaceae, Ruminococcaceae) and host genes (Tnf, Zo1) are named, allowing targeted analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is 20.1 KB, indicating a limited scope of data.

Provenance

Source

figshare

Collection Method

Likely generated from a research study integrating genomic sequencing and animal model experiments.

Freshness

Last updated 2026-04-29 05:37:53; freshness should be verified.