Genomic Determinants of Antifungal Activity in Streptomyces Strain STM-2

Genomic analysis results for Streptomyces melanosporofaciens STM-2, a strain isolated from Chiayi County, Taiwan. The analysis identified 52 biosynthetic gene clusters (BGCs) and specific genes for antifungal enzymes. It was generated by Muhammed Opoku Gyamfi using genome mining and comparative genomics.

Use Cases

• Analyze the 52 predicted biosynthetic gene clusters (BGCs) to identify potential novel antimicrobial compounds.
• Study the identified antifungal enzyme genes (e.g., chitinases, β-1,3-glucanases) for biocontrol application research.
• Examine the high-GC (71%) linear chromosome structure in comparative genomic studies of Streptomyces.
• Use the reported high-resolution Average Nucleotide Identity (ANI) scores for evolutionary analysis of related strains.

Strengths

• Identifies 52 biosynthetic gene clusters (BGCs) including PKS, NRPS, and RiPPs systems.
• Provides genomic data for a novel Streptomyces melanosporofaciens strain with characterized antifungal activity.
• Includes results from structural analysis using AlphaFold2 with high pLDDT scores for unique gene products.

Limitations

• The dataset is very small (14.3 KB), indicating limited scope, likely containing summary results rather than raw genomic sequences.
• Data is specific to a single bacterial strain (STM-2), limiting generalizability.
• The column structure and sample data are unavailable, making direct computational analysis difficult.

Provenance

Source

figshare, authored by Muhammed Opoku Gyamfi.

Collection Method

Generated through genome mining, comparative genomics, and evolutionary analysis of a sequenced bacterial genome.

Freshness

Last updated March 20, 2026.

Geography

Chiayi County, Taiwan (source of the bacterial isolate).