Global Myocarditis Burden in Adolescents and Young Adults, 1990-2021
by Le Zhao·Updated 2mo ago
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Description
349,033 incident cases of myocarditis were recorded globally in 2021 for individuals aged 15-39 years. Le Zhao's analysis from the Global Burden of Disease Study 2021 provides data on incidence, mortality, and disability-adjusted life years (DALYs), stratified by region, country, age, sex, and sociodemographic index (SDI). The study forecasts trends through 2050.
Use Cases
Analyze incidence rate trends by sociodemographic index (SDI) category to identify health disparities across development levels.
Compare mortality and DALYs data stratified by sex and age groups (e.g., 30-34, 35-39 years) to assess demographic risk factors.
Model temporal trends using the provided annual percentage change (APC) and estimated average annual percentage change (EAPC) metrics for forecasting.
Examine regional burden variations, such as the high incident cases in India or deaths in East Asia, for targeted policy planning.
Strengths
Derived from the authoritative Global Burden of Disease (GBD) study 2021.
Provides specific 2021 global estimates: 349,033 incident cases, 3,301 deaths, and 208,644 DALYs, all with 95% uncertainty intervals.
Stratified analysis across five key dimensions: region, country, age, sex, and sociodemographic index (SDI).
Covers a 32-year temporal range from 1990 to 2021 with forecasts to 2050.
Limitations
The dataset is very small (14.5 KB), indicating it contains summary tables, not the underlying raw case-level records.
Uncertainty intervals for all metrics suggest estimates are modeled and not precise counts.
Analysis is restricted to a specific age cohort (15-39 years), limiting generalizability to other populations.
Provenance
Source
Global Burden of Disease (GBD) study 2021.
Collection Method
Systematic analysis of GBD data using Segment regression and log-linear models to calculate APC and EAPC.
Time Range
1990 to 2021, with forecasts to 2050.
Freshness
Last updated March 2026, based on GBD 2021 data.
Geography
Global, with regional and national-level breakdowns.
Data is in a summary XLSX format (14.5 KB); users seeking individual-level patient data must obtain the full GBD microdata separately. License is CC BY 4.0.