Mouse Model Data on Exosome Treatment for IgA Nephropathy

A 44.0 KB PDF file contains data from a study on human umbilical cord mesenchymal stem cell–derived exosomes (hUCMSC-Exos) in an IgA nephropathy-like mouse model. The data likely contains measurements of renal injury markers, gut microbiota composition from 16S rRNA sequencing, and inflammatory signaling markers. The dataset was authored by Yuanyuan He and last updated on 2026-06-01.

Use Cases

• Analyzing associations between gut microbial taxa and renal dysfunction indicators based on correlation data
• Evaluating changes in NLRP3 inflammasome-related gene expression in human IgAN glomeruli based on transcriptomic analysis
• Investigating the effect of exosome treatment on inflammatory markers in stimulated podocytes based on in vitro assay results

Strengths

• Data is derived from a controlled experimental model (IgAN-like mouse model) and in vitro cell assays
• Includes multi-modal analysis covering renal function, histopathology, microbiome sequencing, and transcriptomics
• Associated with a published research methodology described in the background and methods sections

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The 44.0 KB file size suggests a limited scope, likely containing summary or supplementary data rather than raw datasets

Provenance

Source

figshare

Collection Method

Experimental data from an IgAN-like mouse model treated with hUCMSC-Exos, with in vitro podocyte stimulation and analysis of a public human transcriptomic dataset (GSE93798).

Freshness

Last updated 2026-06-01 04:17:35; freshness should be verified