Hypobaric Hypoxia Effects on Lung Dendritic and T-Cell Counts

35.5 KB of experimental data from a study on high-altitude pulmonary edema in rodent models. The dataset contains measurements related to lung dendritic cells and T-cell immunosuppression under hypobaric hypoxia conditions, authored by Xuemei Wei and last updated in March 2026.

Use Cases

• Analyze the relationship between hypobaric hypoxia exposure levels and lung dendritic cell counts in rodent models.
• Investigate the correlation between TNF-α injection and changes in CD4+CD25+ T cell populations.
• Model the immunosuppressive role of T cells, particularly CD4+ subsets, in the progression of HAPE.

Strengths

• Data is directly linked to a published research study with a specific biological hypothesis.
• Includes measurements from both rat and mouse models of high-altitude pulmonary edema.
• Released under a permissive CC BY 4.0 license for reuse.

Limitations

• The dataset is very small at 35.5 KB, indicating limited scope and likely a summary table rather than raw experimental data.
• Specific column names, row counts, and sample data are unavailable, hindering immediate analytical use.
• Data is derived from controlled animal models, which may not directly translate to human physiology.

Provenance

Source

Figshare, authored by Xuemei Wei.

Collection Method

Generated from experimental analysis using single-cell sequencing, flow cytometry, and in vitro co-culture on rodent models.

Freshness

Last updated March 2026.