Providencia huaxiensis PR66: Genomic Data on a Novel NDM-1 ICE

Jia Tao published a genomic dataset on figshare in 2026 detailing a clinical Providencia huaxiensis isolate. The data includes information on a novel 127,074 bp integrative and conjugative element (ICE) harboring the blaNDM-1 carbapenemase gene and multiple other resistance genes. The dataset is 642.5 KB in size and is provided in an XLS file format.

Use Cases

• Analyze the genetic structure of a novel SXT/R391 ICE based on its 127,074 bp sequence and GC content.
• Study the co-location of multiple antibiotic resistance genes, including blaNDM-1, blaOXA-4, and tet(B), on a single mobile genetic element.
• Investigate the site-specific integration of ICEs into bacterial chromosomes based on the prfC locus detail.
• Model the potential for horizontal gene transfer of carbapenem resistance based on the successful conjugation assay to Escherichia coli.

Strengths

• Dataset is associated with a specific, novel genetic element (ICEPhuChn-PR66) with a defined size of 127,074 bp and GC content of 48.6%.
• Includes results from confirmatory assays such as antimicrobial susceptibility testing, ANI/dDDH identification, and conjugation experiments.
• Released under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 642.5 KB size suggests it is a summary table, not the raw sequencing data.

Provenance

Source

figshare, author Jia Tao.

Collection Method

Data derived from whole-genome sequencing and bioinformatics analysis of a clinical bacterial isolate.

Freshness

Last updated 2026-05-22 06:10:41; freshness should be verified.