Bovine Serum Extracellular Vesicle Proteins from Mycoplasma Bovis Infection Study

New Zealand dairy cows were studied to identify protein biomarkers for subclinical Mycoplasma bovis infection. The dataset contains results from a proteomic analysis comparing small extracellular vesicles from serum samples of 45 infected and 49 non-infected cows, identifying 695 non-redundant proteins. The research was conducted by Mallory A. Ross and published on figshare in May 2026.

Use Cases

• Identify diagnostic protein signatures for subclinical Mycoplasma bovis infection based on differential protein abundance analysis.
• Investigate the role of inflammation and complement system proteins in bovine disease states.
• Analyze changes in histone and antimicrobial peptide abundance associated with Mycoplasma bovis infection.
• Develop complementary diagnostic tests for long-term surveillance programs in disease eradication zones.

Strengths

• Includes data from 94 individual cow serum samples (45 infected, 49 controls).
• Identifies 695 non-redundant proteins using liquid chromatography–ion mobility–tandem mass spectrometry.
• Highlights 90 proteins with statistically significant (q-value < 0.05) differential abundance.

Limitations

• Row count and column-level documentation are unknown, requiring manual inspection after download.
• The dataset is very small at 26.9 KB, indicating limited scope.
• The description notes no single specific diagnostic protein candidate was identified.

Provenance

Source

figshare

Collection Method

Small extracellular vesicles were isolated from serum and analyzed via liquid chromatography–ion mobility–tandem mass spectrometry.

Freshness

Last updated 2026-05-15 04:23:06.

Geography

New Zealand