Table 2_Influenza vaccination and cardiovascular and respiratory outcomes in high-risk pop

An umbrella review synthesizing evidence from 14 systematic reviews and meta-analyses published up to December 1, 2025, covering over 230 million participants. The review, authored by Chengyan Jin, critically evaluates the effectiveness and safety of influenza vaccination in high-risk populations for cardiovascular and respiratory complications. It was last updated on May 26, 2026, and is available as a 19.9 KB DOCX file.

Use Cases

• Assessing the association between influenza vaccination and major adverse cardiovascular events based on the review's findings for ischemic heart disease patients.
• Evaluating the evidence for reduced COPD exacerbations linked to vaccination based on the narrative synthesis of respiratory outcomes.
• Analyzing the safety profile of influenza vaccination based on the review's assessment of serious adverse events across the evidence base.
• Prioritizing future research areas based on the identified gaps in evidence certainty for outcomes like stroke.

Strengths

• Evidence synthesis covers over 230 million participants, providing a large-scale perspective.
• Explicitly addresses methodological quality using AMSTAR-2 and evidence certainty using GRADE.
• Includes 14 systematic reviews and meta-analyses, offering a consolidated view of the field.

Limitations

• The dataset is a 19.9 KB DOCX document, indicating a limited scope of raw data or analysis tables.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for quantitative meta-analysis.

Provenance

Source

figshare, authored by Chengyan Jin.

Collection Method

Umbrella review of systematic reviews and meta-analyses identified through PubMed, Embase, and the Cochrane Library.

Time Range

Reviews from database inception to December 1, 2025.

Freshness

Last updated 2026-05-26 06:02:10; freshness should be verified.