Liubao Tea Multi-Omics Analysis: Modulation of Lymphatic Endothelial Cell Metabolism

A multi-omics dataset from a study investigating Liubao tea as a functional fermented food. The data likely contains results from single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking analyses focused on lymphatic endothelial cells. The dataset was created by Xiaoxiao Huang and last updated on 2026-05-18.

Use Cases

• Identify potential therapeutic targets based on the overlapping differentially expressed gene PRKCB.
• Validate molecular docking predictions for Liubao tea components binding to PRKCB.
• Analyze protein-protein interaction networks involving PRKCB, IKBKB, PIK3CG, and GSK3B.
• Correlate in vitro experimental results on cell survival and migration with multi-omics findings.

Strengths

• Integrates results from four distinct methodologies: single-cell transcriptomics, bulk transcriptomics, network pharmacology, and molecular docking.
• Includes specific, statistically significant findings such as a fold change of 24.30 for PRKCB expression (p = 1.44 × 10⁻⁷).
• In vitro experimental validation data is included, showing significant effects on cell survival and migration (p < 0.01, p < 0.001).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 37.4 KB, indicating limited scope and likely summary-level results.

Provenance

Source

figshare

Collection Method

Combined computational multi-omics analysis with in vitro cell culture experiments.

Freshness

Last updated 2026-05-18 05:38:42; freshness should be verified.