Esophageal Cancer Treatment Outcomes from a Single-Center Retrospective Study

January 2011 to December 2018 data compares long-term survival for 490 patients with stage T4N0-3M0 esophageal squamous cell carcinoma treated with surgery plus adjuvant chemoradiotherapy versus definitive chemoradiotherapy. The dataset includes survival outcomes for 108 patients in the S+CRT group and 382 in the dCRT group, with analysis before and after propensity score matching. It was created by Shiwang Wen from a single-institution retrospective cohort study.

Use Cases

• Compare Overall Survival (OS) and Progression-Free Survival (PFS) between the S+CRT and dCRT treatment groups.
• Analyze survival outcomes for the 108 patients in the S+CRT group versus the 382 patients in the dCRT group.
• Replicate propensity score matching (PSM) analysis on the 138 dCRT and 81 S+CRT matched patients to validate treatment effect estimates.
• Model the prognosis of T4N0-3M0 stage esophageal squamous cell carcinoma based on treatment type and patient cohort.

Strengths

• Includes data on 490 patients with a specific cancer stage (T4N0-3M0 ESCC).
• Provides comparative survival metrics (OS, PFS) for two distinct treatment protocols.
• Analysis includes results from a propensity score matched cohort of 219 patients.
• Clear temporal coverage from 2011 to 2018 for a consistent treatment era.

Limitations

• Very small file size (31.5 KB) suggests the data is likely summary statistics or a manuscript table, not a full patient-level dataset.
• Single-center retrospective design limits generalizability and may introduce institutional bias.
• Unknown row and column structure prevents assessment of feature granularity for machine learning.

Provenance

Source

Retrospective cohort study from a single institution, authored by Shiwang Wen.

Collection Method

Clinical data collection from patients treated between January 2011 and December 2018.

Time Range

January 2011 to December 2018

Freshness

Data covers patients through 2018; the record was last updated in 2026.

Geography

Single-center study; specific location unknown.