Pediatric Lung Function Impairment After Tuberculosis Treatment: Meta-Analysis Results

A systematic review and meta-analysis of nine studies investigating lung function outcomes in children after pulmonary tuberculosis treatment. The dataset, authored by Hanhan Wu and last updated in April 2026, contains pooled mean z-scores and standardized mean differences for spirometry measures like FEV₁ and FVC. It was compiled from searches of PubMed, Embase, Web of Science, and Scopus up to October 2025.

Use Cases

• Quantifying the association between childhood TB and reduced lung function based on pooled z-scores for FEV₁ and FVC.
• Comparing post-treatment pulmonary function in children to healthy controls using standardized mean differences (Hedges' g).
• Assessing heterogeneity in lung function outcomes across different studies using reported I² statistics.

Strengths

• Results are derived from a systematic review of nine studies, providing a synthesized evidence base.
• Includes specific pooled effect estimates with 95% confidence intervals for key spirometry parameters.
• Uses a standardized meta-analysis methodology with random-effects models and reports heterogeneity metrics (I² = 55%–98%).

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• The dataset is very small (25.9 KB), indicating it contains summary statistics rather than individual patient-level data.
• The description notes high heterogeneity across studies, suggesting pooled effect sizes should be interpreted as indicative rather than precise.

Provenance

Source

figshare, author Hanhan Wu.

Collection Method

Systematic review and meta-analysis of studies from PubMed, Embase, Web of Science, and Scopus.

Time Range

Literature search up to October 23, 2025.

Freshness

Last updated 2026-04-23 05:35:09; freshness should be verified.