Lymphocyte-to-HDL Ratio and Diabetic Macular Edema in Type 2 Diabetes

A retrospective study of 423 patients with diabetic retinopathy admitted to a single hospital between January 2022 and December 2024. The dataset, shared by Ying Yang on figshare, compares clinical and laboratory information between patients with and without diabetic macular edema (DME). It focuses on the association between the lymphocyte-to-high-density lipoprotein ratio (LHR) and the presence of DME.

Use Cases

• Train a binary classification model to predict diabetic macular edema based on the lymphocyte-to-HDL ratio and other clinical variables.
• Conduct statistical analysis to validate the reported negative linear correlation between LHR and the odds of DME.
• Perform subgroup analyses to explore how the LHR-DME association varies across different patient demographics or comorbidities mentioned in the study.

Strengths

• Includes data from 423 patient records, with 163 in the DME group and 260 in the non-DME group.
• Study period is clearly defined as January 2022 to December 2024.
• Analysis includes multiple statistical methods: logistic regression, quartile-based trend tests, and restricted cubic splines.

Limitations

• Row count for the underlying data table is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is sourced from a single hospital, which may reflect institutional or geographic bias.

Provenance

Source

figshare, author Ying Yang.

Collection Method

Retrospective study gathering clinical and laboratory information from hospital records.

Time Range

January 2022 to December 2024

Freshness

Last updated 2026-05-01 04:17:49; freshness should be verified.