MAFLD and Bone Mineral Density in Type 2 Diabetes Patients

169 patients with type 2 diabetes were analyzed in a retrospective cross-sectional study. The research by Lu Lin investigates the association between metabolic dysfunction-associated fatty liver disease (MAFLD) and lower bone mineral density, exploring a potential indirect link via insulin resistance (HOMA-IR). Results show a statistically significant lower BMD T-score in the MAFLD group compared to the non-MAFLD group.

Use Cases

• Analyze associations between metabolic liver disease and bone health based on BMD T-score data
• Perform statistical mediation analysis based on the described HOMA-IR variable
• Study demographic and metabolic factors in type 2 diabetes patients based on the described anthropometric and metabolic data
• Compare prevalence of osteopenia/osteoporosis between patient groups based on the reported prevalence rates

Strengths

• Includes 169 patient records with demographic, anthropometric, and metabolic data
• Provides specific statistical results, including multivariable regression coefficients (β = -0.562) and mediation analysis effect sizes (β = -0.070)
• Contains clear group comparisons, such as BMD T-score differences (-1.12 vs. -0.50) and prevalence rates (59.0% vs. 33.7%)

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect geographic or institutional bias inherent to a single-center study

Provenance

Source

figshare

Collection Method

Retrospective cross-sectional study collecting demographic, anthropometric, metabolic, and BMD T-score data from patients.

Freshness

Last updated 2026-05-22 04:28:16; freshness should be verified