Maternal Vitamin Trajectories and Infant Birth Weight in a Pregnancy Trial

A secondary analysis of the Exercise Training in Pregnancy Trial (ETIP) study, including 57 mother-infant pairs with overweight or obesity. The dataset contains maternal plasma concentrations of vitamins A, D, and E measured in the second and third trimesters, linked to infant birth weight classifications. It was authored by Astrid Kamilla Stunes and last updated in April 2026.

Use Cases

• Analyze longitudinal changes in maternal vitamin concentrations based on measurements from the second and third trimesters.
• Investigate potential associations between maternal vitamin levels and infant birth weight categories (normal vs. macrosomic).
• Model the prevalence of vitamin insufficiency and deficiency in a pregnant population with overweight or obesity.
• Validate or compare findings on fat-soluble vitamin trajectories in pregnancy using specific HPLC and LC-MS/MS measurements.

Strengths

• Includes specific mean and standard deviation values for vitamin concentrations across trimesters (e.g., retinol: 1.52 to 1.32 µmol/L).
• Reports prevalence rates for clinical conditions: 43.9% macrosomia, 19.3% vitamin A insufficiency, and 31.6% vitamin D deficiency.
• Data is derived from a controlled clinical trial (ETIP) with standardized measurement methods (HPLC, LC-MS/MS).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (17.7 KB), indicating a limited sample size of 57 pairs.

Provenance

Source

Secondary analysis of the Exercise Training in Pregnancy Trial (ETIP) study.

Collection Method

Plasma and serum vitamin measurements via high performance liquid chromatography and liquid chromatography-tandem mass spectrometry.

Time Range

Covers the second and third trimesters of pregnancy.

Freshness

Last updated 2026-04-15 04:37:07; freshness should be verified.

Geography

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