Hypothalamic miRNA Expression in Sunite Sheep Under Three Photoperiod Conditions

Yajing Shao's dataset from 2026 contains miRNA sequencing results from Sunite sheep hypothalami under short, long, and transitional photoperiods. The data includes 57, 47, and 12 differentially expressed miRNAs between condition pairs, with functional annotation linking target genes to reproductive signaling pathways. This 11.4 KB Excel file provides molecular insights into the mechanisms of seasonal estrus.

Use Cases

• Identify differentially expressed miRNAs based on photoperiod condition comparisons described in the study
• Analyze co-expression networks of miRNAs and target genes as referenced in the description
• Investigate enrichment of target genes in reproductive pathways like GnRH, prolactin, VEGF, and Wnt signaling
• Validate predicted interactions for key miRNAs such as oar-miR-370-5p, oar-miR-10b, and oar-miR-3957-3p

Strengths

• Includes specific counts of differentially expressed miRNAs: 57 (SP vs. LP), 47 (SP vs. SLP), and 12 (LP vs. SLP)
• Data is derived from miRNA-sequencing with three biological replicates per experimental group
• Functional annotation links target genes to specific KEGG pathways relevant to reproduction

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is very small at 11.4 KB, indicating limited scope

Provenance

Source

Yajing Shao via figshare

Collection Method

miRNA-sequencing analysis of Sunite sheep hypothalamic tissue

Freshness

Last updated 2026-04-21 05:36:34; freshness should be verified