Table 2_Molecular and cellular adaptations to extended hypothermic oxygenated perfusion in

Morgan K. Moroi's 2026 study provides flow cytometry, RNA sequencing, and metabolomics data from a porcine model comparing static cold storage and hypothermic oxygenated perfusion for heart preservation. The dataset includes results from three experimental groups, including hearts preserved for up to 24 hours. Findings demonstrate measurable populations of viable cardiomyocytes after extended HOPE preservation, contrasting with complete loss after static cold storage.

Use Cases

• Compare cardiomyocyte viability based on flow cytometry data for troponin-positive cells
• Analyze transcriptional shifts from RNA sequencing data between preservation methods
• Investigate metabolic stability and balance from metabolomics profiles
• Evaluate the role of normothermic regional perfusion in pre-preservation harvest

Strengths

• Includes data from three distinct experimental groups enabling comparative analysis
• Multi-modal data encompassing flow cytometry, RNA sequencing, and metabolomics
• Published under a CC-BY-4.0 license allowing for reuse and redistribution

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is from a single animal model (porcine), which may limit generalizability

Provenance

Source

figshare

Collection Method

Experimental data from a controlled porcine model of donation after circulatory death.

Freshness

Last updated 2026-05-25 06:07:06