Influenza Virus Genomes from a Pediatric Hospital in Eastern China, 2024

Eastern China pediatric hospital data includes 425 influenza virus genomes sequenced from 490 specimens collected in 2024. The dataset details co-circulation of A/H1N1, A/H3N2, and B/Victoria lineages, their phylogenetic clades, and antiviral resistance markers. It was authored by Xiaoqing Sun and shared under a CC-BY-4.0 license on figshare.

Use Cases

• Tracking influenza strain co-circulation patterns based on the reported prevalence of A/H1N1, A/H3N2, and B/Victoria.
• Analyzing genetic diversity and phylogenetic clade assignment for seasonal influenza viruses.
• Monitoring antiviral resistance markers such as the oseltamivir resistance marker NA-H275Y mentioned in the results.
• Studying positively selected sites in the hemagglutinin (HA) protein across different influenza lineages.

Strengths

• Contains 425 complete or partial influenza virus genomes from a defined pediatric population.
• Specifies precise genetic clades for circulating strains (e.g., 6B.1A.5a.2a for A/H1N1).
• Reports quantitative antiviral resistance findings, including 7 out of 193 A/H1N1 strains with the NA-H275Y marker.

Limitations

• Row count and column-level documentation are unknown; field semantics must be inferred after download.
• Data is from a single pediatric hospital in Qidong, which may limit geographic generalizability.
• The dataset is 104.7 KB, indicating a limited scope focused on summary or genetic characteristics rather than raw sequence reads.

Provenance

Source

Xiaoqing Sun, via figshare.

Collection Method

Influenza genome enrichment-based whole-genome sequencing performed on antigen-positive specimens.

Time Range

2024

Freshness

Last updated 2026-04-16 05:22:45; freshness should be verified.

Geography

Qidong, eastern China.