Table 2_Neonatal jaundice and the infant gut microbiome: an integrated shotgun metagenomic

Shotgun metagenomic sequencing data from a case-control study of term infants with pathologic jaundice and matched healthy controls in Xinjiang, published on figshare by author Muqing Niu. The dataset includes taxonomic composition, functional gene repertoires, and carbohydrate-active enzyme profiles, analyzed alongside bidirectional Mendelian randomization results. It was last updated on March 18, 2026.

Use Cases

• Identify microbial taxa associated with neonatal jaundice based on relative abundance data for Escherichia coli, Bifidobacterium, and Lactobacillus.
• Analyze functional pathway enrichment in jaundiced infants, including bile acid synthesis and metabolism, and carbohydrate and energy metabolism.
• Investigate causal relationships between microbial metabolic pathways and jaundice risk using the bidirectional Mendelian randomization results.
• Examine shifts in carbohydrate-active enzyme profiles between jaundiced and healthy infant groups.

Strengths

• Data includes results from shotgun metagenomic sequencing, a high-resolution method for microbiome analysis.
• Analysis integrates case-control study findings with bidirectional Mendelian randomization for causal inference.
• Dataset is openly available under a CC-BY-4.0 license, facilitating reuse.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• Data is specific to a study population in Xinjiang, which may limit generalizability to other geographic regions.
• The 2.0 MB file size suggests a relatively small dataset, potentially limiting the scale of analysis.

Provenance

Source

figshare, author Muqing Niu.

Collection Method

Case-control study with stool samples subjected to shotgun metagenomic sequencing, combined with publicly available genome-wide association study summary statistics for Mendelian randomization.

Freshness

Last updated 2026-03-18 07:36:16; freshness should be verified.

Geography

Study conducted in Xinjiang.