Neutrophil-to-HDL Ratio and Stroke Outcomes After Endovascular Therapy

A single-center retrospective cohort study of 367 acute ischemic stroke patients who achieved successful reperfusion after endovascular therapy. The dataset, authored by Ruikai Xu and last updated in April 2026, examines the association between the neutrophil-to-high-density lipoprotein cholesterol ratio (NHR) and 90-day functional outcomes, mortality, and symptomatic intracranial hemorrhage.

Use Cases

• Predicting poor 90-day functional outcome (modified Rankin Scale score 3-6) based on baseline NHR values.
• Assessing the incremental prognostic value of NHR beyond established clinical predictors using logistic regression and AUC comparisons.
• Exploring potential nonlinear relationships between NHR and outcomes using restricted cubic spline analyses.
• Evaluating associations between NHR and secondary outcomes like 90-day mortality and symptomatic intracranial hemorrhage.

Strengths

• Dataset includes 367 patient records from a defined clinical cohort.
• Analysis includes multivariable adjustment and internal validation via bootstrap methods.
• Primary and secondary clinical outcomes (functional outcome, mortality, sICH) are clearly defined.

Limitations

• Row count for the underlying data table is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single-center study, which may limit generalizability and requires external validation.

Provenance

Source

figshare, author Ruikai Xu.

Collection Method

Single-center retrospective cohort study.

Time Range

Temporal coverage of the study is not specified.

Freshness

Last updated 2026-04 15 05:44:22.

Geography

Geographic coverage is not specified, but the study is single-center.