Sleep Apnea and Cytokine Profiles in Parkinson's Disease Patients

54.2% of Parkinson's disease patients in this study were diagnosed with obstructive sleep apnea. The dataset contains cross-sectional clinical, polysomnography, and cytokine profiling data from 48 patients, authored by Carlos Mauricio Oliveira de Almeida and last updated in May 2026. It links OSA severity to specific inflammatory signatures and motor impairment scores in PD.

Use Cases

• Identify inflammatory signatures associated with OSA severity based on cytokine profiles like IL-6 and TNF-α.
• Model the relationship between sleep fragmentation metrics (e.g., oxygen desaturation indices) and motor scores (UPDRS-II/III).
• Analyze network connectivity of immune markers to understand systemic immune reorganization driven by intermittent hypoxia.

Strengths

• Includes multiplex cytokine profiling for 48 patients, enabling analysis of specific immune markers.
• Integrates polysomnography data with clinical evaluations, allowing for multi-modal analysis.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 14.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Cross-sectional study involving clinical evaluation, polysomnography, and cytokine profiling.

Freshness

Last updated 2026-05-18 05:39:39; freshness should be verified.