Table 2_Paired dosimetric comparison of VMAT-based total body and total marrow irradiation

A paired dosimetric analysis of 30 adult acute leukemia patients comparing Volumetric Modulated Arc Therapy (VMAT)-based Total Body Irradiation (TBI) and Total Marrow Irradiation (TMI). The dataset, created by Sevim Sahin and last updated in June 2026, contains plan quality and complexity metrics, including homogeneity index, monitor units, segment number, and modulation factor. Results show TMI provided statistically significant dose reductions to organs at risk while maintaining target coverage.

Use Cases

• Compare plan complexity metrics like monitor units and segment number between TBI and TMI techniques.
• Analyze dose reduction to specific organs at risk, such as the heart, kidneys, liver, and lungs.
• Evaluate the impact of AI-based auto-segmentation on planning efficiency for skeletal target delineation.
• Assess dose homogeneity and plan quality for VMAT-based radiation therapy in leukemia conditioning regimens.

Strengths

• Includes paired data from 30 adult patients, enabling direct comparison of two treatment techniques.
• Plan quality assessed using multiple concrete metrics: homogeneity index, monitor units, segment number, and modulation factor.
• Results show statistically significant (p < 0.001) dose reductions to all evaluated organs at risk with TMI.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 19.3 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Retrospective study using CT datasets from 30 adult acute leukemia patients who received VMAT-based TBI, with corresponding TMI plans generated for comparison.

Freshness

Last updated 2026-06-02 04:28:28; freshness should be verified.