Parabolic Flight Effects on Vaginal and Oral Microbiomes in Women

43.3 KB Excel file contains pre- and post-flight microbiome data from women undergoing parabolic flight. The dataset, authored by Begum Aydogan Mathyk and last updated in May 2026, integrates metagenomic sequencing results with stress biomarkers like cortisol and short-chain fatty acids. It shows significant taxonomic and functional changes in the vaginal microbiome compared to minimal changes in the oral microbiome.

Use Cases

• Train models to predict physiological stress response based on microbiome composition changes.
• Analyze the correlation between specific Lactobacillus species and salivary cortisol levels.
• Compare taxonomic diversity shifts between body sites under acute stress conditions.
• Investigate metabolic pathway enrichment in the vaginal microbiome post-flight.

Strengths

• Integrates multiple data types: metagenomic sequencing results with host stress biomarkers (cortisol, cytokines, SCFAs).
• Provides specific statistical results, such as 57.9% of vaginal species showing significant postflight changes.
• Uses established bioinformatics tools (KneadData, MetaPhlAn, HUMAnN) for analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (43.3 KB), indicating a limited sample size.

Provenance

Source

Begum Aydogan Mathyk via figshare.

Collection Method

Metagenomic shotgun sequencing of pre- and post-parabolic flight samples, analyzed with bioinformatics pipelines.

Freshness

Last updated 2026-05-25 06:05:33; freshness should be verified.