Umbrella Review on Periodontal Disease and Sleep Apnea Association

An umbrella review synthesizes evidence from 11 systematic reviews on the association between periodontal disease (PD) and obstructive sleep apnea (OSA). The document includes methodological quality assessments using AMSTAR-2 and risk of bias evaluations with ROBIS. It was authored by Franz Tito Coronel-Zubiate and registered on the Open Science Framework.

Use Cases

• Extract structured findings on PD-OSA association from the 11 included systematic reviews for meta-synthesis.
• Analyze methodological quality trends using the AMSTAR-2 tool assessments reported in the review.
• Identify variability in diagnostic criteria and study designs noted across the included evidence.
• Use the ROBIS tool risk of bias evaluations to gauge the reliability of the synthesized conclusions.

Strengths

• Synthesizes evidence from 11 systematic reviews identified from 217 initial records.
• Employs standardized appraisal tools (AMSTAR-2 and ROBIS) for quality and bias assessment.
• Published under a permissive CC BY 4.0 license for reuse.

Limitations

• The dataset is a single 670.5 KB document, limiting computational analysis without text extraction.
• Conclusions are based on observational primary studies, preventing causal inference as noted in the review.
• No underlying raw data or tabular columns are provided, only the review's narrative and findings.

Provenance

Source

figshare, authored by Franz Tito Coronel-Zubiate.

Collection Method

Umbrella review methodology, searching multiple databases (PubMed, Cochrane, Scopus, etc.).

Time Range

Literature covered up to December 2025.

Freshness

Last updated March 2026, covering literature up to December 2025.

Geography

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