Table 2_Pharmacological and genetic modulation of IL-32 expression in intestinal epithelia

Experimental data from a study investigating the role of IL-32 in HIV-1 latency and reactivation at the intestinal barrier. The dataset likely contains results from cell culture assays, including measurements of IL-32 mRNA/protein expression and HIV-p24 levels. It was authored by Etiene Moreira Gabriel and last updated on 2026-05-26.

Use Cases

• Analyzing the effects of cytokines (IL-22, IL-26) and compounds (ATRA, RGZ) on IL-32 expression based on the described experimental treatments.
• Investigating the impact of IL-32 knockout on HIV-1 outgrowth in co-culture assays based on the described genetic modulation.
• Comparing transcriptional profiles of control versus IL32KO intestinal epithelial cells based on the mentioned RNA-Sequencing analysis.

Strengths

• Data is associated with a detailed methodological description including CRISPR/Cas9 gene editing and RNA-Sequencing.
• The dataset is licensed under CC-BY-4.0, allowing for open reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 3.9 MB file size suggests a relatively small dataset.

Provenance

Source

figshare

Collection Method

Laboratory experiments using HT-29 intestinal epithelial cells, CRISPR/Cas9 gene editing, and co-culture viral outgrowth assays with CD4+ T-cells from ART-treated people with HIV.

Freshness

Last updated 2026-05-26 07:48:57; freshness should be verified.