Mouse Obesity Study Data on Gut Microbiota and Metabolite Changes

17.3 KB of data from a 17-week mouse study investigating the anti-obesity effects of Portulaca oleracea polysaccharide. The dataset includes obesity-related parameters, gut microbiota profiles, and serum metabolomics from C57BL/6J mice on a high-fat diet. Author Qiang Fu published the data under a CC-BY-4.0 license on figshare in March 2026.

Use Cases

• Correlating specific gut microbiota genera with obesity indices based on the described Firmicutes/Bacteroidetes ratio and other genera.
• Analyzing the relationship between altered metabolites like LacCer (d18:1/12:0) and NDC and metabolic health parameters.
• Modeling the impact of polysaccharide supplementation on lipid profiles and glucose homeostasis in a high-fat diet context.
• Investigating the longitudinal effects of dietary interventions on obesity-related physiological markers over a 17-week period.

Strengths

• Data originates from a controlled 17-week animal experiment with a defined intervention (3.2% POP).
• Analysis includes multiple data layers: physiological parameters, gut microbiota diversity, and serum metabolomics.
• Results are linked to specific, named metabolites and microbial taxa, such as LacCer (d18:1/12:0) and NDC.

Limitations

• The dataset is very small at 17.3 KB, indicating limited scope or summary-level data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

Author Qiang Fu via figshare.

Collection Method

Data collected from a controlled laboratory study on C57BL/6J mice fed a high-fat diet with a polysaccharide supplement.

Time Range

Study duration was 17 weeks; specific calendar dates are not provided.

Freshness

Last updated 2026-03-18 07:38:46; freshness should be verified.