Systematic Review and Meta-Analysis of Nutrition-Based Prognostic Indices in Breast Cancer

A systematic review and meta-analysis of 32 reports comprising 13,120 individuals with breast cancer, authored by Si Chen and published on figshare in 2026. The study evaluates the prognostic utility of the Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) score for clinical outcomes like overall survival and disease-free survival.

Use Cases

• Assessing the association between Prognostic Nutritional Index (PNI) and overall survival (OS) based on pooled hazard ratios.
• Evaluating the link between Controlling Nutritional Status (CONUT) score and disease-free survival (DFS) based on meta-analysis results.
• Investigating heterogeneity in prognostic evidence for nutrition-based indices using subgroup analyses and prediction intervals.

Strengths

• Aggregates data from 32 reports and 13,120 individuals, providing a substantial evidence base.
• Reports pooled effect sizes (hazard ratios and odds ratios) with 95% confidence intervals for multiple clinical outcomes.
• Includes heterogeneity analysis using meta-regression and 95% prediction intervals.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is a 39.7 KB DOCX file, indicating a limited scope focused on the review manuscript rather than raw data.

Provenance

Source

figshare

Collection Method

Systematic literature review and meta-analysis of studies from PubMed, Embase, Web of Science, and Cochrane Library.

Time Range

Literature search from database inception to 20 October 2025.

Freshness

Last updated 2026-05-11 04:17:46; freshness should be verified.